Recombinant human KMT5A protein from NKMAX Co. Ltd.
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| Product Name | Recombinant human KMT5A protein |
| Description | Domain: 195-352aa. Recombinant human KMT5A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 18.9 kDa (165aa). Purity > 85% by SDS-PAGE. KMT5A, also known as N-lysine methyltransferase KMT5A isoform 1, is an enzyme which catalyzes mono-methylation of histone H4 at lysine 20 (H4K20me1). It is implicated in cell-cycle-dependent transcriptional silencing and mitotic regulation in metazoans. It acts as a barrier to prevent cellular senescence through chromatin-mediated regulation of senescence-associated metabolic remodeling. It mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes. The loss of KMT5A concurrently stimulate nucleolar function and retinoblastoma protein-mediated mitochondrial metabolism |
| Size | 10ug, 50ug, 250ug |
| Concentration | 0.25mg/ml (determined by absorbance at 280nm) |
| Applications | SDS-PAGE |
| Other Names | N-lysine methyltransferase KMT5A isoform 1, KMT5A, PR-Set7, SET07, SET8, SETD8 |
| Gene, Accession, CAS # | NCBI: NP_065115, UniProt: Q9NQR1 |
| Catalog # | ATGP3812 |
| Price | $80, $240, $960 |
| Order / More Info | Recombinant human KMT5A protein from NKMAX Co. Ltd. |
| Product Specific References | n/a |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
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