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Product Name | Recombinant human LOX protein |
Description | Domain: 169-417aa. Recombinant human LOX protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 31.4 kDa (272aa). Purity > 85% by SDS-PAGE. LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene |
Size | 20ug, 100ug, 500ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE,Denatured |
Other Names | Protein-lysine 6-oxidase, Lysyl oxidase |
Gene, Accession, CAS # | NCBI: NP_002308, UniProt: P28300 |
Catalog # | ATGP2831 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human LOX protein from NKMAX Co. Ltd. |
Product Specific References | n/a |