Recombinant human Siglec-3/CD33 protein from NKMAX Co. Ltd.
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| Product Name | Recombinant human Siglec-3/CD33 protein |
| Description | Domain: 18-259aa. Recombinant human CD33 protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 29.1 kDa (265aa). Purity > 90% by SDS-PAGE. CD33 is putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha-2, 6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules. This protein induces apoptosis in acute myeloid leukemia (in vitro) |
| Size | 20ug, 100ug, 500ug |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE, Denatured |
| Other Names | SIGLEC-3, SIGLEC3, Sialic acid-binding Ig-like lectin 3, p67, Myeloid cell surface antigen CD33 isoform 1, Myeloid cell surface antigen CD33, FLJ00391, CD33 molecule, CD33 |
| Gene, Accession, CAS # | NCBI: AAH28152, UniProt: P20138 |
| Catalog # | ATGP2584 |
| Price | $80, $240, $720 |
| Order / More Info | Recombinant human Siglec-3/CD33 protein from NKMAX Co. Ltd. |
| Product Specific References | n/a |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
Profile of NKMAX Co. Ltd.