Recombinant human CD45 protein from NKMAX Co. Ltd.
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| Product Name | Recombinant human CD45 protein |
| Description | Domain: 1031-1251aa. Recombinant human PTPRC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 29.6 kDa (257aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. PTPRC, also known as CD45, is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling |
| Size | 4ug, 20ug, 100ug |
| Concentration | 0.25mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE |
| Other Names | Protein tyrosine phosphatase receptor type isoform 1, Protein tyrosine phosphatase, receptor type, isoform 1, LCA, LY5, B220, CD45, T200, GP180 |
| Gene, Accession, CAS # | NCBI: NP_002829.3, UniProt: P08575 |
| Catalog # | ATGP2577 |
| Price | $80, $240, $720 |
| Order / More Info | Recombinant human CD45 protein from NKMAX Co. Ltd. |
| Product Specific References | n/a |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
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