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Product Name | Recombinant human RDBP/NELFE protein |
Description | Domain: 1-380aa. Recombinant human RDBP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 45.4 kDa (400aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher). Purity > 85% by SDS-PAGE. RDBP, also known as NELF-E, is a putative RNA binding protein. This protein is one of the five components of the multisubunit NELF complex that cooperates with DSIF to repress RNA polymerase II elongation. Control of transcription elongation requires a complex interplay between positive transcription elongation factor b and negative transcription elongation factors, DSIF and NELF. DSIF and NELF, act as negative transcription elongation factors by increasing the time the polymerase spends at pause sites. RDBP has a functional RNA-binding domain, whose mutations impair transcription repression without affecting known protein-protein interactions |
Size | 20ug, 100ug, 500ug |
Concentration | 0.25mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Negative elongation factor complex member E, RD RNA-binding protein, RNA-binding protein RD, RD, D6S45, NELF-E, RDP |
Gene, Accession, CAS # | NCBI: NP_002895, UniProt: P18615 |
Catalog # | ATGP0974 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human RDBP/NELFE protein from NKMAX Co. Ltd. |
Product Specific References | n/a |