Recombinant human IL-12 p70 protein from NKMAX Co. Ltd.
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| Product Name | Recombinant human IL-12 p70 protein |
| Description | Domain: 23-328aa(p40)/23-219aa(p35). Recombinant human IL12 protein, fused to His-tag at C-terminus, was expressed in insect cells using baculovirus expression system and purified by using conventional chromatography techniques. MW: 34.6 kDa (p40, 306aa);;23.3 kDa (p35, 203aa) ;;The heterodimeric IL12 has a predicted Molecular weight of 57.9 kDa (509aa). Molecular weight on SDS-PAGE will appear higher. Purity > 90% by SDS-PAGE. IL12 is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. It is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit and a 35 kD subunit. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. IL12 has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen |
| Size | 10ug, 50ug, 250ug |
| Concentration | 0.5mg/ml (determined by absorbance at 280nm) |
| Applications | SDS-PAGE, Bioactivity |
| Other Names | IL12A, IL12B, CLMF p35, CLMF p40, Cytotoxic lymphocyte maturation factor 35 kDa subunit, Cytotoxic lymphocyte maturation factor 40 kDa subunit, Interleukin 12 alpha chain, Interleukin-12 beta chain, NK cell stimulatory factor chain 1, p35, NK cell stimulatory factor chain 2, p40, NKSF1, NKSF2 |
| Gene, Accession, CAS # | NCBI: NP_002178(p40)AAK84425(p35), UniProt: P29460(p40)/P29459(p35) |
| Catalog # | ATGP2843 |
| Price | $80, $240, $960 |
| Order / More Info | Recombinant human IL-12 p70 protein from NKMAX Co. Ltd. |
| Product Specific References | Kim HR, et al. Anti-cancer activity and mechanistic features of a NK cell activating molecule. (Cancer Immunol Immunother. 2009){https://pubmed.ncbi.nlm.nih.gov/19259669/} |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
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