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Product Name | Recombinant human IMP Dehydrogenase 2/IMPDH2 protein |
Description | Domain: 1-514aa. Recombinant human IMPDH2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 58kDa (534aa). Purity > 90% by SDS-PAGE. IMPDH2 belongs to the IMPDH/GMPR family. It catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. Also IMPDH1 and IMPDH2 are targets for the important immunosuppressive drug, mycophenolic acid (MPA) |
Size | 10ug, 50ug, 250ug |
Concentration | 0.5mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Inosine-5'-monophosphate dehydrogenase 2, IMPD2, IMPDH-II |
Gene, Accession, CAS # | NCBI: NP_000875, UniProt: P12268 |
Catalog # | ATGP1274 |
Price | $105, $320, $960 |
Order / More Info | Recombinant human IMP Dehydrogenase 2/IMPDH2 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |