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Product Name | Recombinant human Integrin beta 1/CD29 protein |
Description | Domain: 21-728aa. Recombinant human ITGB1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 79.4 kDa (716aa). Purity > 95% by SDS-PAGE. ITGB1, also known as integrin beta-1 isoform 1A, is the only alpha 1 integrin family adhesion receptor, one of twelve integrins that share the beta 1 subunit, and one of four collagen binding integrins. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This protein is reported to down-regulate EGF-R signaling, increase expression of caveolin-1, reduce production of reactive oxygen species, regulate collagen expression, control MMP collagenase and gelatinase activity, and mediate the renal basement membrane disorder Alport syndrome |
Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
Concentration | 1mg/ml (determined by absorbance at 280nm) |
Applications | SDS-PAGE |
Other Names | CD29, Fibronectin receptor subunit beta, FNRB, Glycoprotein Iia, GPIIA, Integrin beta-1 isoform 1A, ITGB1, MDF2, MSK12, VLA-4 subunit beta, VLAB, VLA-BETA |
Gene, Accession, CAS # | NCBI: NP_002202.2, UniProt: P05556 |
Catalog # | ATGP3549 |
Price | $80, $140, $240, $390, $720, $1200, $1950 |
Order / More Info | Recombinant human Integrin beta 1/CD29 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |