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Product Name | Recombinant human LRG1 protein |
Description | Domain: 36-347aa. Recombinant human LRG1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 35.4 kDa (321aa). Purity > 95% by SDS-PAGE. LRG1, also known as leucine-rich alpha-2-glycoprotein, is a member of leucine-rich repeat (LRR) family. It is neutrophilic expressed during granulocyte differentiation. It has been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. It binds directly to the TGF-beta accessory receptor endoglin, which, in the presence of TGF-beta1, results in promotion of the pro-angiogenic Smad1/5/8 signaling pathway. It promotes proliferation and inhibits apoptosis in colorectal cancer cells via RUNX1 activation. It is a key physiological regulator of dendrite complexity of hippocampal pyramidal neurons. It physically interacts with TrkB and attenuates BDNF signaling |
Size | 4ug, 20ug, 100ug |
Concentration | 0.5mg/ml (determined by absorbance at 280nm) |
Applications | SDS-PAGE |
Other Names | Leucine-rich alpha-2-glycoprotein, LRG1, HMFT1766, LRG |
Gene, Accession, CAS # | NCBI: NP_443204, UniProt: P02750 |
Catalog # | ATGP3755 |
Price | $80, $240, $960 |
Order / More Info | Recombinant human LRG1 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |