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Product Name | Recombinant human IL-18R alpha/IL18R1 protein |
Description | Domain: 19-329aa. Recombinant human IL18R1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 62.7 kDa (550aa). Purity > 90% by SDS-PAGE. IL18R1, also known as interleukin 18 receptor 1, is an interleukin receptor of the immunoglobulin superfamily. This protein contain three Ig-like C2-type (immunoglobulin-like) domains and on TIR domain. It shares numerous immuno-regulatory functions with IL12. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. Also, this receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. It binds to the agonist leads to the activation of NF-kappa-B, but does not bind IL1A or IL1B beta |
Size | 10ug, 50ug, 250ug |
Concentration | 0.5mg/ml (determined by absorbance at 280nm) |
Applications | SDS-PAGE |
Other Names | Interleukin-18 receptor 1, CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, IL-1Rrp, IL1R-rp, Interleukin-18 receptor alpha, IL-18R-alpha, IL-18Ralpha, CD218a, IL1RRP, IL-1Rrp |
Gene, Accession, CAS # | NCBI: NP_003846, UniProt: Q13478 |
Catalog # | ATGP3821 |
Price | $80, $240, $960 |
Order / More Info | Recombinant human IL-18R alpha/IL18R1 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |