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Product Name | Recombinant human Kallikrein 2/KLK2 protein |
Description | Domain: 25-261aa. Recombinant human KLK2 protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 28.5 kDa (260aa). Purity > 85% by SDS-PAGE. KLK2 is a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. KLK2 is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants |
Size | 20ug, 100ug, 500ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE, Denatured |
Other Names | Kallikrein related peptidase 2, Glandular kallikrein-1, hGK-1, Tissue kallikrein-2, Prostatic kallikrein 2 |
Gene, Accession, CAS # | NCBI: NP_005542, UniProt: P20151 |
Catalog # | ATGP2175 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human Kallikrein 2/KLK2 protein from NKMAX Co. Ltd. |
Product Specific References | Lee SW, et al. Simple and robust antibody microarray-based immunoassay platform for sensitive and selective detection of PSA and hK2 toward accurate diagnosis of prostate cancer. (Sensing and Bio-Sensing Research, 2015){https://doi.org/10.1016/j.sbsr.2015.01.003.};;Lee SW, et al. A Highly Sensitive Porous Silicon (P-Si)-Based Human Kallikrein 2 (hK2) Immunoassay Platform toward Accurate Diagnosis of Prostate Cancer. (Sensors (Basel). 2015){https://www.ncbi.nlm.nih.gov/pubmed/26007739};;Lee SW, et al. Porous silicon microarray for simultaneous fluorometric immunoassay of the biomarkers prostate-specific antigen and human glandular kallikrein 2. (Microchim Acta. 2016){https://doi.org/10.1007/s00604-016-1986-1} |