Recombinant human CD40/TNFRSF5 protein from NKMAX Co. Ltd.
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| Product Name | Recombinant human CD40/TNFRSF5 protein |
| Description | Domain: 21-193aa. Recombinant human CD40, fused to hIgG-His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques. MW: 46.1kDa (412aa). Purity > 95% by SDS - PAGE. CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily. It transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglubiln secretion. CD40 is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells |
| Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
| Concentration | 1mg/ml (determined by Absorbance at 280nm) |
| Applications | SDS-PAGE |
| Other Names | Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, p50, CD40L receptor, CDw40 |
| Gene, Accession, CAS # | NCBI: NP_001241.1, UniProt: P25942 |
| Catalog # | ATGP4007 |
| Price | $136, $243, $320, $534, $931, $1591, $2648 |
| Order / More Info | Recombinant human CD40/TNFRSF5 protein from NKMAX Co. Ltd. |
| Product Specific References | n/a |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
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