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Product Name | Recombinant human IL-17E/IL-25 protein |
Description | Domain: 33-177aa. Recombinant human IL-17E/IL-25, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques. MW: 17.8kDa (154aa). Purity > 95% by SDS - PAGE. IL-25, also known as IL-17E, belongs to the IL-17 cytokine family. It support the Th2 immune response, and has been shown to induce the production of IL-4, IL-5 and IL-13. This is in contrast to other IL-17 family members which promote Th1- and Th17-biased inflammation. Because IL-25 promotes the development of a Th2 immune response, it acts to protect against several bowel infections caused by helminths. It is also referred to as the regulator of IL-9 production. IL-25 has been shown to increase the production of IL-9 in Th9 cells. Another function of this protein is the activation of natural lymphoid cells. IL-25 and IL-33 are the most potent activators of ILC2. IL-25 has potent antitumor activity in vivo in several human cancers including melanoma, breast, lung, colon, and pancreatic cancers, suggesting the potential clinical use of IL-17E as an anticancer agent |
Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
Concentration | 0.5mg/ml (determined by Absorbance at 280nm) |
Applications | SDS-PAGE, Bioactivity |
Other Names | interleukin-25 isoform 1, interleukin 25, IL17E, IL-17E, IL25, IL-25, interleukin-17E, interleukin-25, Macroprhagleukin-25 isoform 2 |
Gene, Accession, CAS # | NCBI: NP_073626.1, UniProt: Q9H293 |
Catalog # | ATGP4018 |
Price | $140, $250, $330, $550, $960, $1640, $2730 |
Order / More Info | Recombinant human IL-17E/IL-25 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |