Recombinant human SIRP alpha/CD172a protein from NKMAX Co. Ltd.
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| Product Name | Recombinant human SIRP alpha/CD172a protein |
| Description | Domain: 27-373aa. Recombinant human SIRP alpha, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques. MW: 39kDa (356aa). Purity > 95% by SDS - PAGE. SIRP alpha is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRP alpha interacts with a broadly expressed transmembrane protein CD47. This interaction negatively controls effector function of innate immune cells such as host cell phagocytosis. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. It was found to participate in signal transduction mediated by various growth factor receptors |
| Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
| Concentration | 1mg/ml (determined by Absorbance at 280nm) |
| Applications | SDS-PAGE, Bioactivity |
| Other Names | SIRPA, Tyrosine-protein phosphatase non-receptor type substrate 1 isoform 1, SHP substrate 1, SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Bit, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MyD-1 antigen, Signal-regulatory protein alpha-1, Sirp-alpha-1, Signal-regulatory protein alpha-2, Sirp-alpha-2, Signal-regulatory protein alpha-3, Sirp-alpha-3, p84, CD172a, BIT, MFR, MYD1, PTPNS1, SHPS1,SIRP |
| Gene, Accession, CAS # | NCBI: NP_542970.1, UniProt: P78324 |
| Catalog # | ATGP4069 |
| Price | $130, $240, $320, $530, $930, $1590, $2650 |
| Order / More Info | Recombinant human SIRP alpha/CD172a protein from NKMAX Co. Ltd. |
| Product Specific References | n/a |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
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