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Product Name | Recombinant human Desert Hedgehog/Dhh N-terminus protein |
Description | Domain: 23-198aa. Recombinant DHH protein was expressed in E. coli and purified by using conventional chromatography techniques. MW: 22 kDa (197aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. DHH belongs to the hedgehog family. The C-terminal domain displays an autoproteolysis activity and a cholesterol transferase activity. The N- terminal domain is the active species in both local and long-range signaling, whereas the C-terminal domain has no signaling activity. This protein is produced by Sertoli cells and may be involved in both male gonadal differentiation and perineurial development. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy |
Size | 20ug, 100ug, 500ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | desert hedgehog preproprotein, Drosophila, HHG-3, MGC35145, Desert hedgehog protein N-product, DHH, desert hedgehog preproprotein Desert hedgehog, Desert hedgehog (Drosophila) homolog, Desert hedgehog homolog (Drosophila), Desert hedgehog protein precursor. |
Gene, Accession, CAS # | NCBI: NP_066382, UniProt: O43323 |
Catalog # | DHH0901 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human Desert Hedgehog/Dhh N-terminus protein from NKMAX Co. Ltd. |
Product Specific References | n/a |