Recombinant human 14-3-3 sigma protein from NKMAX Co. Ltd.
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| Product Name | Recombinant human 14-3-3 sigma protein |
| Description | Domain: 1-248aa. Recombinant human 14-3-3 sigma was expressed in E. coli and purified by using conventional chromatography techniques. MW: 27.7 kDa (248aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. 14-3-3 sigma, also known as Stratifin (SFN), belong to the 14-3-3 family. The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. 14-3-3 sigma was identified as an epithelial cell marker and appeared to function as a tumor suppressor whose expression can be down regulated via methylation. Loss of 14-3-3 sigma expression results in a defective G2/M phase checkpoint and appears to contribute to both epithelial and non-epithelial tumorigenesis |
| Size | 20ug, 100ug, 500ug |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE |
| Other Names | stratifin, Epithelial cell marker protein 1, HME1, YWHAS, SFN, 14-3-3 sigma |
| Gene, Accession, CAS # | NCBI: NP_006133, UniProt: P31947 |
| Catalog # | ATGP0435 |
| Price | $70, $210, $625 |
| Order / More Info | Recombinant human 14-3-3 sigma protein from NKMAX Co. Ltd. |
| Product Specific References | Arakawa N, et al. Stratifin as a Novel Diagnostic Biomarker in Serum for Diffuse Alveolar Damage. (Research Square. 2021){https://doi.org/10.21203/rs.3.rs-690487/v1};;Arakawa N, et al. Serum stratifin and presepsin as candidate biomarkers for early detection of COVID-19 disease progression. (J Pharmacol Sci. 2022){https://pubmed.ncbi.nlm.nih.gov/35926945/} |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
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