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Product Name | Recombinant human SOD2/Mn-SOD protein |
Description | Domain: 25-222aa. Recombinant human SOD2 protein was expressed in E. coli and purified by using conventional chromatography techniques. MW: 24.4 kDa (219aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. SOD2 is a member of the iron/manganese superoxide dismutase family. It is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this protein have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer |
Size | 20ug, 100ug, 500ug |
Concentration | 0.5mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE, Enzyme Activity |
Other Names | Superoxide dismutase [Mn] mitochondrial, IPOB, MNSOD, MVCD6, Superoxide dismutase [Mn], mitochondrial IPO B, Manganese SOD, Manganese superoxide dismutase, Mn SOD, SOD 2, SOD2, Superoxide dismutase [Mn] mitochondrial, Superoxide dismutase 2 mitochondrial, Superoxide Dismutase-2 |
Gene, Accession, CAS # | NCBI: NP_001019636.1, UniProt: P04179 |
Catalog # | ATGP0512 |
Price | $70, $210, $625 |
Order / More Info | Recombinant human SOD2/Mn-SOD protein from NKMAX Co. Ltd. |
Product Specific References | Kwon MJ, et al. Superoxide dismutase 3 suppresses hyaluronic acid fragments mediated skin inflammation by inhibition of toll-like receptor 4 signaling pathway: superoxide dismutase 3 inhibits reactive oxygen species-induced trafficking of toll-like receptor 4 to lipid rafts. (Antioxid Redox Signal. 2012) {https://pubmed.ncbi.nlm.nih.gov/21957979/};;Kwon MJ, et al. Superoxide dismutase 3 controls adaptive immune responses and contributes to the inhibition of ovalbumin-induced allergic airway inflammation in mice. (Antioxid Redox Signal. 2012){https://pubmed.ncbi.nlm.nih.gov/22583151/};;Peskin AV, Winterbourn CC. Assay of superoxide dismutase activity in a plate assay using WST-1. (Free Radic Biol Med. 2017){https://pubmed.ncbi.nlm.nih.gov/28017897/} |