Recombinant human Insulysin/IDE protein from NKMAX Co. Ltd.
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| Product Name | Recombinant human Insulysin/IDE protein |
| Description | Domain: 42-1019aa. Recombinant human Insulysin/IDE, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 114kDa (984aa). Purity > 90% by SDS-PAGE. Insulysin/IDE, also known insulin-degrading enzyme, is a zinc metallopeptidase of the inverzincin family. This enzyme catalyses the degradation reaction of insulin, glucagon and other polypeptides. It is present in mammals and in many arthropods such as the fly Drosophila melanogaster. It is also expressed in many tissues, with the highest levels in liver, kidney, brain, and testis. It has been shown to degrade the amyloid beta peptide, which polymerizes into the plaques associated with Alzheimers disease. Therefore, the deficiency of IDE activity may contribute to the pathogenesis of type 2 diabetes mellitus and Alzheimers disease |
| Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
| Concentration | 0.5mg/ml (determined by Absorbance at 280nm) |
| Applications | SDS-PAGE, Enzyme Activity |
| Other Names | Insulin-degrading enzyme, insulin-degrading enzyme isoform 1, Abeta-degrading protease, Insulin protease, Insulysin, IDE |
| Gene, Accession, CAS # | NCBI: NP_004960.2, UniProt: P14735 |
| Catalog # | ATGP4128 |
| Price | $150, $270, $370, $610, $1060, $1830, $3040 |
| Order / More Info | Recombinant human Insulysin/IDE protein from NKMAX Co. Ltd. |
| Product Specific References | n/a |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
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