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Product Name | Recombinant M. tuberculosis ESAT6 protein |
Description | Domain: 1-95aa. Recombinant Mycobacterium tuberculosis CDC1551 ESAT6 protein, fused to His-tag at C-terminus, was expressed in Baculovirus and purified by using conventional chromatography techniques. MW: 11 kDa (104aa). Purity > 90% by SDS-PAGE. ESAT6, the 6 kDa early secretory antigenic target of Mycobacterium tuberculosis, is a secretory protein and potent T cell antigen. ESAT6 has been shown to directly bind to the TLR2 receptor, inhibiting downstream signal transduction. Recently it was shown that ESAT6 is very potential as diagnostic for differentiation between the mycobacterial infection and BCG vaccination |
Size | 10ug, 50ug, 250ug |
Concentration | 0.5mg/ml (determined by BCA assay) |
Applications | SDS-PAGE |
Other Names | Early secretory antigenic target 6 kDa, Early secretory antigenic target, 6 kDa, |
Gene, Accession, CAS # | NCBI: NP_338543.1, UniProt: P9WNK6 |
Catalog # | ATGP1480 |
Price | $105, $320, $960 |
Order / More Info | Recombinant M. tuberculosis ESAT6 protein from NKMAX Co. Ltd. |
Product Specific References | Satake Y, et al. Type-1 polarised dendritic cells are a potent immunogen against Mycobacterium tuberculosis. (Int J Tuberc Lung Dis. 2017){https://pubmed.ncbi.nlm.nih.gov/28399967/};;Ouyang W, et al. Enabling electrical biomolecular detection in high ionic concentrations and enhancement of the detection limit thereof by coupling a nanofluidic crystal with reconfigurable ion concentration polarization. (Lab Chip. 2017){https://pubmed.ncbi.nlm.nih.gov/28983543/} |