Recombinant human IL-33 protein from NKMAX Co. Ltd.

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Product NameRecombinant human IL-33 protein
DescriptionDomain: 112-270aa. Recombinant human IL-33(C-terminal fragment) was expressed in E.coli and purified by using conventional chromatography techniques. MW: 18.1 kDa (160aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. Interleukin 33 (IL-33) is a 32kDa proinflammatory cytokine that may also regulate gene transcription in producer cells. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1
Size10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg
Concentration1mg/ml (determined by Bradford assay)
ApplicationsSDS-PAGE, Bioactivity
Other NamesInterleukin-33, Interleukin-1 family member 11, IL-1F11, Nuclear factor from high endothelial venules, NF-HEV, DVS27-related protein, DVS27, C9orf26
Gene, Accession, CAS #NCBI: NP_254274, UniProt: O95760
Catalog #ILC0701
Price$100, $160, $290, $480, $920, $1440, $2500
Order / More InfoRecombinant human IL-33 protein from NKMAX Co. Ltd.
Product Specific ReferencesIto R, et al. A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis. (JCI Insight. 2018){https://pubmed.ncbi.nlm.nih.gov/30385714/}
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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