Recombinant MERS-CoV Spike S1 Subunit protein from NKMAX Co. Ltd.
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| Product Name | Recombinant MERS-CoV Spike S1 Subunit protein |
| Description | Domain: 18-751aa. Recombinant MERS-CoV Spike S1 Subunit, fused to His-tag at C-terminus, was expressed in insect cell, and purified by using conventional chromatography techniques. MW: 82.0kDa(740aa). Purity > 85% by SDS - PAGE. MERS-CoV, which causes the Middles East Respiratory Syndrome (MERS), belongs to a family of viruses known as coronaviruses. MERS-CoV was first identified in the Kingdom of Saudi Arabia in 2012, which is a single and positive stranded RNA virus. Dromedary camels are widely considered as the source of the transmission of MERS-CoV. The rate of human transmission among household contacts of MERS patients has been approximately 5 % based on serological analysis. MERS-CoV has four structural proteins, known as the S (spike), E (envelope), M (membrane), and N (nucleocapsid) proteins. The spike protein, responsible for allowing the virus to attach to and fuse with the membrane of a host cell and is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion. MERS-CoV S mediates viral attachment and fusion to human cells via human cellular receptor DPP4, also known as CD26. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity |
| Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
| Concentration | 0.25mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE, Bioactivity |
| Other Names | Middle East respiratory syndrome coronavirus, Human betacoronavirus 2c EMC/2012, MERS-CoV, MERS, MERS-CoV S1 P, Spike1 glycoprotein, S1 glycoprotein, S1, Spike S1 Subunit protein, S1 Subunit |
| Gene, Accession, CAS # | NCBI: AFS88936, UniProt: K0BRG7 |
| Catalog # | ATGP3980 |
| Price | $120, $220, $290, $480, $850, $1450, $2420 |
| Order / More Info | Recombinant MERS-CoV Spike S1 Subunit protein from NKMAX Co. Ltd. |
| Product Specific References | Goo J, et al. Characterization of novel monoclonal antibodies against MERS-coronavirus spike protein. (Virus Res. 2020){https://pubmed.ncbi.nlm.nih.gov/31945421/} |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
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P: +82-31-8017-8114
F: +82-31-8017-8124
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http://www.nkmaxbio.com
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