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Product Name | Recombinant human SHMT1 protein |
Description | Domain: 1-483aa. Recombinant human SHMT1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 55.2 kDa (503aa). Purity > 95% by SDS-PAGE. Serine hydroxymethyltransferase 1, also known as SHMT1, belongs to the SHMT family. This protein is cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5 10-methylene tetrahydrofolate. Also, SHMT1 preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate and inhibits |
Size | 20ug, 100ug, 500ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Serine hydroxymethyltransferase 1, CSHMT, SHMT |
Gene, Accession, CAS # | NCBI: AAH07979, UniProt: P34896 |
Catalog # | ATGP1310 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human SHMT1 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |