Recombinant mouse Adiponectin (globular domain) protein from NKMAX Co. Ltd.
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| Product Name | Recombinant mouse Adiponectin (globular domain) protein |
| Description | Domain: 111-247aa. Adiponectin/Acrp30 (247amino acids) is adipocyte complement-related protein of 30kDa and exclusively expressed in differentiated adipocytes. Adiponectin (Acrp30) is a member of the complement factor C1q family and consists of signal sequence, Non-homologous sequence, collagen domain and globular domain (gAcrp30). Adiponectin (Acrp30) expression is reduced in a variety of obese and insulin-resistant states in human, monkeys and mice. Injection of Acrp30 (247aa) or gAcrp30 (globular domain) lowers serum glucose and free fatty acid level in mice. The globular domain of adiponectin/acrp30 (amino acid residues, 111-247, gAcrp30) was overexpressed in E. coli and purified by using conventional chromatography techniques. MW: 16 kDa (138aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. |
| Size | 20ug, 100ug, 500ug |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE |
| Other Names | ADIPOQ, ACDC, ACRP30, APM1, GBP28, Adiponectin globular domain, Mouse, Adipocyte, C1q and collagen domain-containing protein, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipose most abunda, Adiponectin, 30 kDa adipocyte complement related protein, ACRP 30, Adipocyte C1q and collagen domain containing protein, Adipocyte complement related 30 kDa protein, Adipocyte complement related protein of 30 kDa, Adipose most abundant gene transcript 1, APM 1, GBP 28, Gelatin binding protein, |
| Gene, Accession, CAS # | NCBI: NP_033735, UniProt: Q60994 |
| Catalog # | ADI3001 |
| Price | $55, $170, $505 |
| Order / More Info | Recombinant mouse Adiponectin (globular domain) protein from NKMAX Co. Ltd. |
| Product Specific References | Singh AK, et al. Orally active osteoanabolic agent GTDF binds to adiponectin receptors, with a preference for AdipoR1, induces adiponectin-associated signaling, and improves metabolic health in a rodent model of diabetes. (Diabetes. 2014){https://pubmed.ncbi.nlm.nih.gov/24848063/};;Khan MP, et al. Pathophysiological Mechanism of Bone Loss in Type 2 Diabetes Involves Inverse Regulation of Osteoblast Function by PGC-1α and Skeletal Muscle Atrogenes: AdipoR1 as a Potential Target for Reversing Diabetes-Induced Osteopenia. (Diabetes. 2015){https://pubmed.ncbi.nlm.nih.gov/25633418/};;Singh AK, et al. Small molecule adiponectin receptor agonist GTDF protects against skeletal muscle atrophy. (Mol Cell Endocrinol. 2017){https://pubmed.ncbi.nlm.nih.gov/27645900/} |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
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P: +82-31-8017-8114
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