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Product Name | Recombinant human SGTA protein |
Description | Domain: 1-313aa. Recombinant SGTA protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 35.1 kDa (321aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. SGTA, also known as SGT or hSGT, is a ubiquitously expressed protein that contains three TPR protein-protein interaction repeats. This protien is believed to function as a component of the androgen receptor (AR) -chaperone-cochaperone complex, acting as a cochaperone involved in androgen signaling. In addition, SGTA functions as a cochaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. On the basis of its role in apoptosis and androgen signaling, SGTA is a potential candidate for PCOS (polycystic ovary syndrome), a disorder characterized by androgen excess, obesity and menstrual disturbances |
Size | 20ug, 100ug, 500ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Small glutamine-rich tetratricopeptide repeat-containing protein alpha, alphaSGT, hSGT, SGT, Small glutamine-rich tetratricopeptide repeat-containing protein alpha Small glutamine rich tetratricopeptide repeat TPR containing alpha, uBP, Vpu binding protein. |
Gene, Accession, CAS # | NCBI: NP_003012, UniProt: O43765 |
Catalog # | ATGP0533 |
Price | $70, $210, $625 |
Order / More Info | Recombinant human SGTA protein from NKMAX Co. Ltd. |
Product Specific References | n/a |