Description | Domain: 48-454aa. Recombinant human LY9, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 45.9 kDa (416aa). Purity > 90% by SDS-PAGE. LY9, as known as T-lymphocyte surface antigen Ly-9 isoform, is a type 1 transmembrane glycoprotein in the SLAM subgroup of the CD2 family. This protein consists of an extracellular domain with two lg-like V-set and two lg-like truncated C2-set domains. It is expressed on T and B cells, thymocytes, and more weakly on NK cells. Homophilic binding between LY9 molecules is mediated by the N-terminal lg-like domain. Also, this protein knockout mice show minimally impaired immune responses, suggesting functional redundancy with other molecules |
Other Names | T-lymphocyte surface antigen Ly-9 isoform, LY9, CD229, hly9, mLY9, SLAMF3, CD229 Cell surface molecule Ly-9, Cell surface molecule Ly9, hly9, LY 9, Ly9, LY9_HUMAN, Lymphocyte antigen 9, mLY9, Signaling lymphocytic activation molecule 3, SLAM family member 3, SLAMF3, T lymphocyte surface antigen Ly9 precursor, T-lymphocyte surface antigen Ly-9 |