Recombinant human CD40/TNFRSF5 protein from NKMAX Co. Ltd.
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| Product Name | Recombinant human CD40/TNFRSF5 protein |
| Description | Domain: 21-193aa. Recombinant human CD40 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 21.6 kDa (196aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. CD40 is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis |
| Size | 10ug, 50ug, 250ug |
| Concentration | 0.25mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE |
| Other Names | Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, p50, CD40L receptor, CDw40 |
| Gene, Accession, CAS # | NCBI: NP_001241.1, UniProt: P25942 |
| Catalog # | ATGP2615 |
| Price | $80, $240, $720 |
| Order / More Info | Recombinant human CD40/TNFRSF5 protein from NKMAX Co. Ltd. |
| Product Specific References | n/a |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
Profile of NKMAX Co. Ltd.