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Product Name | Recombinant human IL-10R alpha/IL10RA protein |
Description | Domain: 22-235aa. Recombinant human IL10RA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 25.2 kDa (220aa). Purity > 85% by SDS-PAGE. IL10RA, also known as Interleukin-10 receptor subunit alpha, is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. It has been shown to interact with Interleukin 10 and Janus kinase 1 |
Size | 10ug, 50ug, 250ug |
Concentration | 0.2mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Interleukin 10 receptor subunit alpha, IL-10 receptor subunit alpha, IL-10R subunit alpha, IL-10RA, CD210, CDw210a, Interleukin-10 receptor subunit 1, IL-10R subunit 1, IL-10R1, HIL-10R |
Gene, Accession, CAS # | NCBI: NP_001549, UniProt: Q13651 |
Catalog # | ATGP3074 |
Price | $80, $240, $960 |
Order / More Info | Recombinant human IL-10R alpha/IL10RA protein from NKMAX Co. Ltd. |
Product Specific References | n/a |