Recombinant human LCAT protein from NKMAX Co. Ltd.

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Product NameRecombinant human LCAT protein
DescriptionDomain: 25-440aa. Recombinant human LCAT protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 49.8 kDa (441aa). Purity > 85% by SDS-PAGE. LCAT (lecithin-cholesterol acyltransferase), also known as phosphatidylcholine-sterol O-acyltransferase, belongs to the AB hydrolase superfamily. LCAT is responsible for the esterification of the free cholesterol of plasma lipoproteins. This enzyme is converts free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol), which is then sequestered into the core of a lipoprotein particle, eventually making the newly synthesized HDL spherical and forcing the reaction to become unidirectional since the particles are removed from the surface. It is central enzyme in the extracellular metabolism of plasma lipoproteins and required for remodeling high-density lipoprotein particles into their spherical forms
Size20ug, 100ug, 500ug
Concentration0.5mg/ml (determined by Bradford assay)
ApplicationsSDS-PAGE, Denatured
Other NamesPhosphatidylcholine-sterol acyltransferase, lecithin-cholesterol acyltransferase, phosphatidylcholine-sterol O-acyltransferase
Gene, Accession, CAS #NCBI: NP_000220, UniProt: P04180
Catalog #ATGP1899
Price$80, $240, $720
Order / More InfoRecombinant human LCAT protein from NKMAX Co. Ltd.
Product Specific ReferencesIshibashi R, et al. Immune-mediated acquired lecithin-cholesterol acyltransferase deficiency: A case report and literature review. (J Clin Lipidol. 2018){https://pubmed.ncbi.nlm.nih.gov/29937398/}
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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