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Product Name | Recombinant human Fumarase/FH protein |
Description | Domain: 44-510aa. Recombinant Fumarase was expressed in E. coli and was purified by conventional chromatography techniques. MW: 50.2 kDa (467aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor |
Size | 20ug, 100ug, 500ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE, Enzyme Activity |
Other Names | Fumarate hydratase, FH, HLRCC, LRCC, MCL, MCuL1, Fumarate hydratase Fumarase, Fumarate hydratase mitochondrial, MCuL 1, Multiple hereditary cutaneous leiomyomata. |
Gene, Accession, CAS # | NCBI: NP_000134, UniProt: P07954 |
Catalog # | FMR0905 |
Price | $55, $170, $505 |
Order / More Info | Recombinant human Fumarase/FH protein from NKMAX Co. Ltd. |
Product Specific References | n/a |