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Product Name | Recombinant human CD28 protein |
Description | Domain: 19-152aa. Recombinant human CD28, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 42.4 kDa (376aa). Purity > 90% by SDS-PAGE. CD28, also known as T-cell-specific surface glycoprotein CD28 isoform 1, is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 in particular). CD28/B7 interaction has been shown to prevent apoptosis of activated T cells via the up-regulation of bcl-XL. It ligation has also been shown to regulate Th1/Th2 differentiation |
Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
Concentration | 1mg/ml (determined by absorbance at 280nm) |
Applications | SDS-PAGE, Bioactivity |
Other Names | T-cell-specific surface glycoprotein CD28 isoform 1, CD28, Tp44 |
Gene, Accession, CAS # | NCBI: NP_006130.1, UniProt: P10747 |
Catalog # | ATGP3603 |
Price | $80, $130, $210, $230, $300, $520, $860 |
Order / More Info | Recombinant human CD28 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |