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Product Name | Recombinant human C4BPB protein |
Description | Domain: 18-252aa. Recombinant human C4BPB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 29kDa (260aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain of this protein assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C |
Size | 20ug, 100ug, 500ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Complement component 4 binding protein beta, Complement component 4 binding protein, beta, C4BP |
Gene, Accession, CAS # | NCBI: NP_000707, UniProt: P20851 |
Catalog # | ATGP1664 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human C4BPB protein from NKMAX Co. Ltd. |
Product Specific References | Sugimoto M, et al. Increased expression of Protein S in eyes with diabetic retinopathy and diabetic macular edema. (Sci Rep. 2021){https://pubmed.ncbi.nlm.nih.gov/34001977/};;Urawa M, et al. Protein S is protective in pulmonary fibrosis. (J Thromb Haemost. 2016){https://pubmed.ncbi.nlm.nih.gov/27172994/};;Yasuma T, et al. Amelioration of Diabetes by Protein S. (Diabetes. 2016){https://pubmed.ncbi.nlm.nih.gov/27207541/} |