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Product Name | Recombinant human Cofilin 1/CFL1 protein |
Description | Domain: 1-166aa. Recombinant human Cofilin, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 20kDa (186aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. Cofilin is a family of actin-binding proteins which disassembles actin filaments. It is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus |
Size | 20ug, 100ug, 500ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | 18 kDa phosphoprotein(p18), CFL, CFL1, Cofilin 1, Cofilin 1 non muscle, Cofilin non muscle isoform, P18 |
Gene, Accession, CAS # | NCBI: NP_005498, UniProt: P23528 |
Catalog # | COF0701 |
Price | $105, $320, $960 |
Order / More Info | Recombinant human Cofilin 1/CFL1 protein from NKMAX Co. Ltd. |
Product Specific References | Wang Y, et al. AMP-activated protein kinase/myocardin-related transcription factor-A signaling regulates fibroblast activation and renal fibrosis. (Kidney Int. 2018){https://pubmed.ncbi.nlm.nih.gov/28739141/} |