Recombinant mouse TRANCE/RANKL/TNFSF11 protein from NKMAX Co. Ltd.
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| Product Name | Recombinant mouse TRANCE/RANKL/TNFSF11 protein |
| Description | Domain: 158-316aa. Recombinant Mouse TRANCE protein was expressed in E. coli and purified by using conventional chromatography. MW: 17.9 kDa (160aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. TRANCE, also known as tumor necrosis factor ligand superfamily member 11, is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. TRANCE also has a function in the immune system, where it is expressed by T helper cells and is thought to be involved in dendritic cell maturation. TRANCE is important in bone metabolism. This natural and necessary surface-bound molecule (also known as CD254) found on osteoblasts serves to activate osteoclasts, which are the cells involved in bone resorption |
| Size | 20ug, 50ug, 100ug |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE |
| Other Names | Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE, CD254 |
| Gene, Accession, CAS # | NCBI: NP_035743, UniProt: O35235 |
| Catalog # | ATGP3851 |
| Price | $190, $340, $510 |
| Order / More Info | Recombinant mouse TRANCE/RANKL/TNFSF11 protein from NKMAX Co. Ltd. |
| Product Specific References | Park KH, et al. Zinc inhibits osteoclast differentiation by suppression of Ca2+-Calcineurin-NFATc1 signaling pathway. (Cell Commun Signal. 2013) {https://pubmed.ncbi.nlm.nih.gov/24088289/} |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
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http://www.nkmaxbio.com
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