Mikrogen Diagnostik recomWell Parvovirus B19 IgM ELISA Kit from QED BIOSCIENCE INC.
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| Product Name | Mikrogen Diagnostik recomWell Parvovirus B19 IgM ELISA Kit |
| Description | Enzyme immunoassay with antigens produced by recombinant techniques for the detection of IgG and IgM antibodies against the human Parvovirus B19 Product is intended for research use. Human Parvovirus B19 occurs endemically worldwide. At intervals of several years, it causes epidemics in small areas from late fall to early summer, affecting kindergartens and schools in particular. The infection rate in children is between 15 and 30 % and in adults about 60 %.The virus has a single stranded genome of about 5.6 kB and is packed in an icosahedral capsid, without a lipid layer, with a diameter of 22 nm. The two capsid proteins VP-1 and VP-2 are coded from the same reading frame. VP-1 is distinguished from VP-2 only by an additional N-terminal fragment. Furthermore, a nonstructural protein NS-1 is synthesized, which is required for virus replication and propagation in the cell.Clinical spectrum of a Parvovirus B19 infection:Fifth disease (erythema infectiosum): It progresses in 20 % of cases without symptoms or with flu-like symptoms. Apart from the exanthema, polyarthralgia and a generalized swelling of the lymph nodes can occur occasionally.Aplastic crisis in patients suffering from hemolytic anemias.Spontaneous abortion/hydrops fetalis after infection during pregnancy.Persistent infection in immunosuppressed persons with chronic anemia and bone marrow depression.Genetically engineered VP-1 antigen as well as VP-2 particles are used in the recomWell Parvovirus B19 tests. With the use of VP-2 particles the presentation of conformational epitopes in addition to the linear epitopes is achieved. |
| Size | 96 tests |
| Concentration | n/a |
| Applications | ELISA |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | 4405 |
| Price | $479 |
| Order / More Info | Mikrogen Diagnostik recomWell Parvovirus B19 IgM ELISA Kit from QED BIOSCIENCE INC. |
| Product Specific References | n/a |
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