Mikrogen Diagnostik recomWell Chlamydia pneumoniae IgA ELISA Kit from QED BIOSCIENCE INC.
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| Product Name | Mikrogen Diagnostik recomWell Chlamydia pneumoniae IgA ELISA Kit |
| Description | Enzyme immunoassay based on Chlamydia pneumoniae specific antigen (COMC) for the detection of IgG, IgM or IgA antibodies against Chlamydia pneumoniae in human serum and plasma Product is intended for research use. Chlamydia pneumoniae is a widespread, obligately intracellular bacterium which affects the respiratory tract. In Germany the prevalence in women and men in the sixth decade of life is estimated >50% and >70% respectively. Most infections are asymptomatic, a few infections cause mild symptoms like sinusitis or bronchitis. Nevertheless, we also see severe courses of infections associated with asthma, pneu-moniae, rarely coming along with arthritis or atherosclerosis. Chlamydiae reproduce in a biphasic development cycle showing extracellular, infectious elementary bodies and intracellular, metabolically active but not infectious reticular bodies. This kind of reproduction facilitates persistence formation and chronical infection.In diagnostics direct detection of chlamydia antigen (cultivation and PCR techniques) and indirect proof by antibody detection are used. Cultivation of Chlamydiae however is quite time-consuming and PCR is not well standardized. Reliable differentiation between acute and persistent infection remains difficult. In Chlamydia pneumoniae serology the Micro Immune Fluorescence (MIF) assay is considered as the gold standard. This technique is labor-intensive, requires experience and is therefore reserved for special laboratories. To avoid unnecessary antibiotic therapy there is a need to provide accurate analytics for routine diagnostics to be guided by the gold standard MIF and reflecting the clinical situation.To detect antibodies against the pathogen the recomWell Chlamydia pneumoniae is using antigens from the outer membrane complex of Chlamydia pneumoniae (COMC). With the objective to discriminate mild, clini-cally inconspicuous infections from clinically relevant infections the test was built up on a MIF cut-off value of 1:32. The recomWell Chlamydia pneumoniae shows an excellent specificity compared to other commercially available ELISA test systems. In healthy blood donors the recomWell Chlamydia pneumoniae detects an IgG prevalence of 39.5% and an IgA prevalence of 4.5% respectively. |
| Size | 96 tests |
| Concentration | n/a |
| Applications | ELISA |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | 6106 |
| Price | $462 |
| Order / More Info | Mikrogen Diagnostik recomWell Chlamydia pneumoniae IgA ELISA Kit from QED BIOSCIENCE INC. |
| Product Specific References | n/a |
QED BIOSCIENCE INC.
QED BIOSCIENCE INC.
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