Edit |   |
---|---|
Product Name | Mikrogen Diagnostik recomLine Parvovirus B19 IgG (Avidity) Lateral Strip Test Kit |
Description | Strip-Immunoassay with antigens produced by recombinant techniques for the detection of IgG and IgM antibodies against human Parvovirus B19 Product is intended for research use. Human Parvovirus B19 occurs endemically world-wide. At intervals of several years, it causes epidemics in small areas from late fall to early summer, affecting kindergartens and schools in particular.Its surface is formed by a protein envelope which consists of two polypeptides (VP-1 and VP-2). VP-1 differs from VP-2 only by an additional N-terminal fragment. Furthermore, a non-structural protein (NS-1) is synthesized, which is required for virus replication.Clinical spectrum of a Parvovirus B19 infection:Fifth disease (erythema infectiosum): It progresses in 20% of cases without symptoms or with flu-like symptoms. Apart from the exanthema, polyarthralgia and a generalized swelling of the lymph nodes can occur occasionally.Aplastic crisis in patients suffering from hemolytic anemias.Spontaneous abortion/hydrops fetalis after infection during pregnancy.Persistent infection in immunosuppressed persons with chronic anemia and bone marrow depression.By the kind of antigen pattern and the avidity determination of IgG antibodies the recomLine Parvovirus B19 provides an indication of the time of infection. The determination of antibodies against the NS-1 antigen can be helpful in the clarification of persistent Parvovirus B19 infections. With the use of VP-2 particles the presentation of conformational epitopes in addition to the linear epitopes is achieved. |
Size | 20 tests |
Concentration | n/a |
Applications | Lateral Strip Assay |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | 4472 |
Price | $550 |
Order / More Info | Mikrogen Diagnostik recomLine Parvovirus B19 IgG (Avidity) Lateral Strip Test Kit from QED BIOSCIENCE INC. |
Product Specific References | n/a |