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Product Name | Glutathione S-Transferase Omega 1 (GST-01) (Western Blot Control) |
Description | Purity Single band on Western blot. GSTO1 is a member of the theta class glutathione S transferase-like (GSTTL) protein family. GSTO1 is expressed in a wide range of human tissues and exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities and also catalyzes the reduction of monomethylarsonate, an intermediate in the pathway of arsenic biotransformation. GSTO1 protects from oxidative stress, a risk factor for Alzheimer disease, vascular dementia and stroke. Several polymorphisms in the coding regions of the human GSTO1 have been identified. A polymorphism causing an alanine-to aspartate (A140D) substitution in amino acid 140 produces a variant with lowered enzyme activities in the arsenic biotransformation. RANDOX recombinant GSTO1 140D comprises a 241 amino acid fragment (1-241) corresponding to the GSTO1 140D mutant mature protein, which is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use. |
Size | 10µg |
Concentration | n/a |
Applications | RUO |
Other Names | Recombinant protein. GSTTLp28; P28, glutathione S-transferase omega 1-1; glutathione transferase omega; glutathione transferase omega 1; glutathione-S-transferase like, Monomethyl Arsenous Reductase. |
Gene, Accession, CAS # | n/a |
Catalog # | RCP9193 |
Price | $100 |
Order / More Info | Glutathione S-Transferase Omega 1 (GST-01) (Western Blot Control) from RANDOX LABORATORIES LTD. |
Product Specific References | Withbread, A. K. et al., Methods in Enzymology 2005; 401: 78-99 Koelsch, H. et al., Neurology 2004; 63 : 2255-2260 |