Pregnancy Associated Plasma Protein-1 (PAPP-1A) from RANDOX LABORATORIES LTD.
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| Product Name | Pregnancy Associated Plasma Protein-1 (PAPP-1A) |
| Description | Purity >95% by SDS-PAGE. PAPP-A is a large zinc binding protein, which acts as a metalloprotease and has been shown to cleave insulin-like growth factor binding protein-4. PAPP-A can act as a regulator of IGF bioactivity in several biological systems, including the human ovary and cardiovascular systems. Recent studies have shown that levels are elevated in patients with unstable angina or acute myocardial infarction. PAPP-A is also produced in high concentrations during pregnancy and is released into the maternal circulation. Low levels of PAPP-A have been linked with a number of foetal chromosomal abnormalities, as well as pre-eclampsia and stillbirth. |
| Size | 100µg |
| Concentration | n/a |
| Applications | RUO |
| Other Names | Recombinant protein. Pappalysin-1; Pregnancy-Associated Plasma Protein-1; Insulin-like growth factor-dependent IGF binding protein-4, EC 3.4.24.79; IGF-dependent IGFBP-4 protease; IGFBP4ase. |
| Gene, Accession, CAS # | n/a |
| Catalog # | RCP9038 |
| Price | $468 |
| Order / More Info | Pregnancy Associated Plasma Protein-1 (PAPP-1A) from RANDOX LABORATORIES LTD. |
| Product Specific References | Conover, C.A. et al., 2004 Development 131 (5) 1187- 1196 |
RANDOX LABORATORIES LTD.
RANDOX LABORATORIES LTD.
55 Diamond Road,
Crumlin, County Antrim, BT29 4QY UNITED KINGDOM
P: +44 (0) 28 9442 2413
https://www.randox.com/bioreagents-overview/
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