Integrin-Linked Kinase (ILK) from RANDOX LABORATORIES LTD.

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Product NameIntegrin-Linked Kinase (ILK)
DescriptionPurity >95% by SDS-PAGE. Integrin-linked kinase (ILK1) is a serine/threonine protein kinase, containing 4 ankyrin-like repeats. ILK1 interacts with the cytoplasmic domains of integrin β1 and β3 subunits as well as several adaptors and signalling proteins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. ILK1 has been reported to regulate a number of biological properties including anchorage independent cell cycle progression, tumour cell invasion and apoptosis. Over-expression of ILK1 has been documented in a wide variety of human malignancies. RANDOX recombinant ILK1 comprises a 452 amino acid fragment (1-452) corresponding to the mature ILK1 full-length protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
Size1mg
Concentrationn/a
ApplicationsRUO
Other NamesRecombinant protein. ILK-1, ILK-2, 59 kDa serine/threonine-protein kinase, p59, p59ILK.
Gene, Accession, CAS #n/a
Catalog #RCP9299
Price$2294
Order / More InfoIntegrin-Linked Kinase (ILK) from RANDOX LABORATORIES LTD.
Product Specific ReferencesHannigan G.E. et al Nature. 1996. 379 (6560) : 91-6. Marotta A. et al, BJC 2003 88 :1755-1762
RANDOX LABORATORIES LTD.
RANDOX LABORATORIES LTD.
RANDOX LABORATORIES LTD.
55 Diamond Road,
Crumlin, County Antrim, BT29 4QY UNITED KINGDOM
P: +44 (0) 28 9442 2413


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