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Product Name | Rat CD80 - B7-1 ELISA Kit |
Description | Specificity: Natural and recombinant rat CD80. There is no detectable cross-reactivity with other relevant proteins. The protein CD80(Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7-1. The cDNA for B7-1 predicts a type I membrane protein, i.e., one synthesized with a signal peptide that is cleaved upon translocation across the endoplasmic membrane. The protein is predicted to contain 2 extracellular domains structurally similar to those of Ig, a hydrophobic transmembrane region, and a short cytoplasmic domain. The CD80 and CD86 genes encode B7-1 and B7-2, respectively, which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4. |
Size | 1 kit |
Concentration | n/a |
Applications | ELISA |
Other Names | Activation B7-1 antigen, B7, BB1, CD80, CD80_HUMAN, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD82 |
Gene, Accession, CAS # | CD80, Gene ID: 25408, NCBI: NP_037058.1, UniProt: O35187 |
Catalog # | KOA0412 |
Price | $589 |
Order / More Info | Rat CD80 - B7-1 ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |