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Product Name | Rat Cystatin C ELISA Kit |
Description | Specificity: Natural and recombinant rat Cystatin C. There is no detectable cross-reactivity with other relevant proteins. Cystatin C or cystatin 3(formerly gamma trace, post-gamma-globulin or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, was originally described as a constituent of normal cerebrospinal fluid(CSF) and of urine from patients with renal failure. Cystatin 3 has a low molecular weight(approximately 13.3 kilodaltons), and it is removed from the bloodstream by glomerular filtration in the kidneys. In mouses, all cells with a nucleus(cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and bodily fluids. Cystatin C, which belongs to the type II cystatin gene family, is a potent inhibitor of lysosomal proteinases(enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases(it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Moreover, cystatin C is involved in network reorganization in the epileptic dentate gyrus. |
Size | 1 kit |
Concentration | n/a |
Applications | ELISA |
Other Names | ARMD11, bA218C14.4 (cystatin C), Cst3, Cystatin-3, Cystatin-C, CYTC_HUMAN, Gamma-trace, Neuroendocrine basic polypeptide, Post-gamma-globulin |
Gene, Accession, CAS # | CST3, Gene ID: 25307, NCBI: NP_036969.1, UniProt: P14841 |
Catalog # | KOA0632 |
Price | $589 |
Order / More Info | Rat Cystatin C ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |