Human ADA ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC.

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Product NameHuman ADA ELISA Kit
DescriptionSpecificity: Natural and recombinant human ADA. There is no detectable cross-reactivity with other relevant proteins. Adenosine Deaminase (also known as adenosine aminohydrolase, or ADA) is an enzyme involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. ADA in humans is involved in the development and maintenance of the immune system. However, ADA association has also been observed with epithelial cell differentiation, neurotransmission, and gestation maintenance. It has also been proposed that ADA, in addition to adenosine breakdown, stimulates release of excitatory amino acids and is necessary to the coupling of A1 adenosine receptors and heterotrimeric G proteins. Adenosine deaminase deficiency leads to pulmonary fibrosis, suggesting that chronic exposure to high levels of adenosine can exacerbate inflammation responses rather than suppressing them. It has also been recognized that adenosine deaminase protein and activity is upregulated in mouse hearts that overexpress HIF-1 alpha, which in part explains the attenuated levels of adenosine in HIF-1 alpha expressing hearts during ischemic stress.
Size1 kit
Concentrationn/a
ApplicationsELISA
Other Namesada, ADA1, ADA 1, Adenosine aminohydrolase, Adenosine deaminase
Gene, Accession, CAS #ADA, Gene ID: 100, NCBI: NP_000013.2, UniProt: P00813
Catalog #KOA0873
Price$589
Order / More InfoHuman ADA ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

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