Human APP ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC.

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Product NameHuman APP ELISA Kit
DescriptionSpecificity: Natural and recombinant human APP. There is no detectable cross-reactivity with other relevant proteins. Amyloid precursor protein(APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates beta amyloid(Abeta), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. APP undergoes posttranslational proteolytic processing by alpha-, beta-, and gamma-secretases. Alpha-secretase generates soluble amyloid protein, while beta- and gamma-secretases generate APP components with amyloidogenic features. These 2 processing pathways are mutually exclusive.
Size1 kit
Concentrationn/a
ApplicationsELISA
Other NamesA4 amyloid protein, A4|A4_HUMAN, AAA, ABETA, ABPP, AD 1, Alzheimer disease 1, Alzheimer disease amyloid protein, Amyloid beta A4 protein, Amyloid beta A4 protein precursor isoform b, Amyloid beta A4 protein precursor isoform c, Amyloid beta A4 protein precursor isoform a, Amyloid of aging and alzheimer disease, APP I, Beta amyloid peptide, Cerebral vascular amyloid peptide, CTFgamma, CVAP, Human mRNA for amyloid A4 precursor of Alzheimer's disease, PreA4, Protease nexin II
Gene, Accession, CAS #APP, Gene ID: 351, NCBI: NP_000475.1, UniProt: P05067
Catalog #KOA0375
Price$639
Order / More InfoHuman APP ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

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