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Product Name | Human ADAMTS4 ELISA Kit |
Description | Specificity: Natural and recombinant human ADAMTS4. There is no detectable cross-reactivity with other relevant proteins. ADAMTS4, A disintegrin and metalloproteinase with thrombospondin motifs 4 is an enzyme that in humans is encoded by the ADAMTS4 gene. ADAMTS4 is a member of the large ADAMTS family of zinc-dependent proteases. The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. |
Size | 1 kit |
Concentration | n/a |
Applications | ELISA |
Other Names | A disintegrin and metalloproteinase with thrombospondin motifs 4, A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 4, A disintegrin like and metalloprotease with thrombospondin type 1 motif 4, ADAM metallopeptidase with thrombospondin type 1 motif 4, ADAM TS 4, ADAM TS4, ADAM-TS 4, ADAM-TS4, ADAMTS2, ADAMTS4, ADAMTS4 protein, ADMP 1, ADMP-1, ADMP1, Aggrecanase1, ATS4_HUMAN, KIAA0688 |
Gene, Accession, CAS # | ADAMTS4, Gene ID: 9507, NCBI: NP_001307265.1, UniProt: O75173 |
Catalog # | KOA0831 |
Price | $589 |
Order / More Info | Human ADAMTS4 ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |