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Product Name | Human AXL ELISA Kit |
Description | Specificity: Natural and recombinant human AXL. There is no detectable cross-reactivity with other relevant proteins. Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. It is in close vicinity to the bcl3 oncogene, which is at 19q13.1-q13.2. The Axl gene is evolutionarily conserved between vertebrate species. This gene has two different alternatively spliced transcript variants. |
Size | 1 kit |
Concentration | n/a |
Applications | ELISA |
Other Names | Adhesion related kinase, AI323647, Ark, AXL oncogene, AXL receptor tyrosine kinase, AXL transforming gene, AXL transforming sequence/gene, JTK11, Oncogene AXL, Tyro7, Tyrosine protein kinase receptor UFO, UFO |
Gene, Accession, CAS # | AXL, Gene ID: 558, NCBI: NP_001690.2, UniProt: P30530 |
Catalog # | KOA0376 |
Price | $589 |
Order / More Info | Human AXL ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |