Human CD105 ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC.
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| Product Name | Human CD105 ELISA Kit |
| Description | Specificity: Natural and recombinant human CD105. There is no detectable cross-reactivity with other relevant proteins. CD105, also called Endoglin, is a homodimeric membrane glycoprotein primarily associated with human vascular endothelium. It is also found on bone marrow proerythroblasts, activated monocytes, and lymphoblasts in childhood leukemia. Endoglin is a component of the transforming growth factor-beta(TGFB) receptor complex and binds TGFB1 with high affinity.1 CD105 gene is mapped to 9q34.1. The coding region of the gene contains 14 exons.2 The protein consists of a homodimer of 180 kDA with disulfide links. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. Furthermore, it also has a role in the balance of ALK1 and ALK5 signaling to regulate endothelial cell proliferation.3 Moreover, the elevated expression of endoglin in the surgically excised CNVMs suggested a persisting postmitotic activation in an advanced stage of neovascular tissue.4 The standard product used in this kit is extracellular part of recombinant huma. |
| Size | 1 kit |
| Concentration | n/a |
| Applications | ELISA |
| Other Names | AI528660, AI662476, CD 105, CD105 antigen, Cell surface MJ7/18 antigen, END, Endoglin, ENG, FLJ41744, HHT1, ORW, ORW1, Osler Rendu Weber syndrome 1, OTTMUSP00000012838, OTTMUSP00000012839, RP11 228B15.2, RP23 17P12.4, S endoglin, Transmembrane glycoprotein |
| Gene, Accession, CAS # | ENG, Gene ID: 2022, NCBI: NP_000109.1, UniProt: P17813 |
| Catalog # | KOA0371 |
| Price | $639 |
| Order / More Info | Human CD105 ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.