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Product Name | Rat FAS-L ELISA Kit |
Description | Specificity: Natural and recombinant rat FAS-L. There is no detectable cross-reactivity with other relevant proteins. FAS Ligand (FASL) is a 40 kDa type II membrane protein belonging to the tumor necrosis factor family, which induces apoptosis by binding to its receptor, Fas. The human FasL gene consists of approximately 8.0 kb and is split into four exons. This gene consists of 281 amino acids with a calculated M(r) of 31,759 and was mapped on chromosome 1q23. It has an identity of 76.9% at the amino acid sequence level with mouse FasL. The FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signaling pathway has been shown to participate in immune escape and tumor genesis. FAS and FASL triggered apoptosis pathway plays an important role in human carcinogenesis. This system may also play a role in modulating the genetic susceptibility of mouse strains to develop T-cell lymphoblastic lymphomas. |
Size | 1 kit |
Concentration | n/a |
Applications | ELISA |
Other Names | Apoptosis (APO 1) antigen ligand 1, Apoptosis antigen ligand, APT1LG1, APTL, CD178, CD95 L, CD95 ligand, CD95L, CD95L protein, Fas antigen ligand, FASL, FASLG, TNF superfamily member 6, TNFSF6, Tumor necrosis factor (ligand) superfamily member 6, Tumor necrosis factor ligand superfamily member 6 |
Gene, Accession, CAS # | FASLG, Gene ID: 25385, NCBI: NP_037040.1, UniProt: P36940 |
Catalog # | KOA0633 |
Price | $589 |
Order / More Info | Rat FAS-L ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |