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Product Name | Human Ficolin-3 ELISA Kit |
Description | Specificity: Natural and recombinant human Ficolin-3. There is no detectable cross-reactivity with other relevant proteins. Ficolin-3, also known as HAKA1, is a protein that in humans is encoded by the FCN3 gene. It is mapped to 1p36.11. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Ficolin-3 is expressed as a 35-kD protein that reacts with systemic lupus erythematosus sera. Ficolin-3 does not bind fibronectin(FN1), elastin(ELN), or zymosan, and the lectin activity of the Ficolin-3 is calcium independent. Homozygosity for the variant in the FCN3 gene results in a recessive complement deficiency syndrome. |
Size | 1 kit |
Concentration | n/a |
Applications | ELISA |
Other Names | Collagen/fibrinogen domain containing lectin 3 p35, Collagen/fibrinogen domain containing protein 3, FCN 3, FCNH, Ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen), Ficolin (collagen/fibrinogen domain containing) 3, Ficolin 3, H ficolin, HAKA1, Hakata antigen, MGC22543 |
Gene, Accession, CAS # | FCN3, Gene ID: 8547, NCBI: NP_003656.2, UniProt: O75636 |
Catalog # | KOA0743 |
Price | $589 |
Order / More Info | Human Ficolin-3 ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |