Human CD169 - SIGLEC-1 ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC.
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| Product Name | Human CD169 - SIGLEC-1 ELISA Kit |
| Description | Specificity: Natural and recombinant human CD169. There is no detectable cross-reactivity with other relevant proteins. SIGLEC-1, also known as Sialoadhesin or CD169, is a cell adhesion molecule found on the surface of certain cells of the immune system called macrophages. This gene is mapped to 20p13. It belongs to the immunoglobulin superfamily(IgSF). Since sialoadhesin binds sialic acids with its N-terminal IgV-domain, it is also a member of the SIGLEC family. The localization and expression of SIGLEC-1 in humans has altered coincident with the evolutionary loss of Neu5Gc. SIGLEC-1-positive macrophages have a dual physiologic function. They act as innate 'flypaper' by preventing the systemic spread of lymph-borne pathogens and as critical gatekeepers at the lymph-tissue interface that facilitate the recognition of particulate antigens by B cells and initiate humoral immune responses. |
| Size | 1 kit |
| Concentration | n/a |
| Applications | ELISA |
| Other Names | CD169, CD169 antigen, dJ1009E24.1, DKFZp667F058, FLJ00051, FLJ00055, FLJ00073, FLJ00411, FLJ32150, Sialic acid binding Ig like lectin 1, Sialic acid binding immunoglobulin like lectin 1, Sialic acid-binding Ig-like lectin 1, Sialoadhesin, Siglec 1, Siglec-1, Siglec1, SN, SN_HUMAN |
| Gene, Accession, CAS # | SIGLEC1, Gene ID: 6614, NCBI: NP_075556.1, UniProt: Q9BZZ2 |
| Catalog # | KOA0778 |
| Price | $789 |
| Order / More Info | Human CD169 - SIGLEC-1 ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
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https://www.rockland.com/
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