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Product Name | Human CD23 - FCER2 ELISA Kit |
Description | Specificity: Natural and recombinant human CD23. There is no detectable cross-reactivity with other relevant proteins. CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the FCE2 gene was assigned to 19p13.3. CD23(FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor. |
Size | 1 kit |
Concentration | n/a |
Applications | ELISA |
Other Names | BLAST 2, BLAST-2, C-type lectin domain family 4 member J, CD23, CD23 antigen, CD23A, CLEC4J, Fc fragment of IgE low affinity II receptor for (CD23), Fc-epsilon-RII, FCE2, Fcer2, FCER2_HUMAN, IGEBF, Immunoglobulin E-binding factor, Low affinity immunoglobulin epsilon Fc receptor, Low affinity immunoglobulin epsilon Fc receptor soluble form, Lymphocyte IgE receptor |
Gene, Accession, CAS # | FCER2, Gene ID: 2208, NCBI: NP_001193948.2, UniProt: K3W4U1 |
Catalog # | KOA0549 |
Price | $589 |
Order / More Info | Human CD23 - FCER2 ELISA Kit from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |